Research Article
Developing a Regulatory Framework for the Safe Integration of Engineered Synthetic Microbial Communities (SynComs) in Agriculture: Lessons from Global Practices ![](https://ecoevopublisher.com/templates/images/OA.gif)
2 National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya, 572025, Hainan, China
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GMO Biosafety Research, 2024, Vol. 15, No. 2
Received: 17 Feb., 2024 Accepted: 29 Mar., 2024 Published: 06 Apr., 2024
This study explores the development of a regulatory framework for the safe integration of SynComs in agriculture by drawing lessons from global practices. Key findings indicate that the design and application of SynComs should be informed by a deep understanding of plant-microbe interactions, microbial ecology, and the specific traits of beneficial microbes. Computational tools, including machine learning, play a crucial role in optimizing SynCom compositions for desired plant phenotypes. Case studies highlight the importance of reproducibility, stability, and the ecological impact of SynComs. By synthesizing insights from various research efforts, this study provides a roadmap for developing a regulatory framework that ensures the safe and effective use of SynComs in agriculture, leveraging global practices and cutting-edge research to address current challenges and opportunities.
(The advance publishing of the abstract of this manuscript does not mean final published, the end result whether or not published will depend on the comments of peer reviewers and decision of our editorial board.)
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. Wujun Jin
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. Synthetic microbial communities (SynComs)
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