Guanli Fu

Hainan Institute of Biotechnology, Haikou, 570206, Hainan, China
Author    Correspondence author
GMO Biosafety Research, 2024, Vol. 15, No. 4   
Received: 06 May, 2024    Accepted: 22 Jun., 2024    Published: 08 Jul., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study systematically summarizes the research progress and practical results of using rice natural insect-resistant germplasm resources and genetic engineering technology to fight pests, and analyzes the application prospects of natural insect-resistant mechanisms (including behavioral inhibition, adverse nutrition, and tolerance) and modern technologies such as exogenous gene introduction (such as Bt protein), RNA interference (RNAi) and CRISPR/Cas gene editing. Studies have shown that natural insect-resistant resources represented by the Bph series of resistance genes and genetic engineering resistance technologies (such as Bt rice and RNAi rice) have shown significant field insect-resistant effects and can effectively reduce the use of pesticides; however, they also face challenges such as insufficient resistance persistence, potential ecological risks and public acceptance. In the future, it is urgent to strengthen the multi-resistance "gene pyramid" strategy, conditionally induced insect-resistant gene expression, and the integration of ecological safety assessment and green control technology. This study provides an important theoretical basis and technical guidance for the sustainable control of rice insect pests, which is of great significance to ensuring food security and sustainable development of the ecological environment.

Rice; Insect pests; Natural resistance; Genetic engineering; Sustainable control