Ping Shan

Biotechnology Research Center, Cuixi Academy of Biotechnology, Zhuji, 311800, China
Author    Correspondence author
GMO Biosafety Research, 2024, Vol. 15, No. 4   
Received: 05 Jun., 2024    Accepted: 16 Jul., 2024    Published: 02 Aug., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

This study focuses on ecological balance. By systematically analyzing typical cases in agricultural production (such as insect-resistant crops), ecological conservation (such as gene-driven mosquito species and endangered animal protection) and public health (such as control of mosquito-mediated transmission), the potential impact of gene-edited organisms on ecosystems in terms of population structure, biological interactions and genetic diversity was evaluated. The study found that insect-resistant gene-edited crops may indirectly affect non-target species and soil ecological functions; gene-driven mosquito species may disturb wetland ecological networks and cause ecological imbalance; and the release of enhanced endangered species individuals may bring risks of genetic pollution and niche changes. Therefore, it is necessary to construct a multi-scale ecological risk assessment indicator system and monitoring network, implement a scientific risk-response model, and strengthen international cooperation and public participation to ensure the safety and sustainability of the ecological application of gene editing technology. This study provides a theoretical basis and management strategy reference for the responsible promotion of the development of gene editing technology, and has important scientific and social significance for maintaining ecological security and sustainable development.

Gene editing; Ecological balance; CRISPR-Cas; Ecological risk assessment; Gene drive