Feature Review

The Changing Face of Influenza: How the Virus Evolves to Evade Immunity  

yeping han
1 Zhuji Jianmin Pharmacy, Zhuji, 311800, Zhejiang, China; 2 Institute of Life Sciences, Jiyang Colloge of Zhejiang A&F University, Zhuji, 311800, Zhejiang, China
Author    Correspondence author
International Journal of Super Species Research, 2024, Vol. 14, No. 2   
Received: 19 Feb., 2024    Accepted: 28 Mar., 2024    Published: 10 Apr., 2024
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

The influenza virus, particularly influenza A virus, exhibits a high degree of variability and evolves continuously through antigenic drift and antigenic shift, leading to seasonal influenza outbreaks and occasional pandemics on a global scale. This study provides an in-depth understanding of how the influenza virus evades detection by the immune system during its evolution and explores the impact of these evolutionary mechanisms on vaccine development and public health strategies. The results show that the influenza virus rapidly mutates and reassorts its genes, producing new strains that can evade host immunity and spread across different species, thereby increasing the challenges of controlling influenza. The evolution of the influenza virus not only challenges existing vaccines and antiviral treatment strategies but also underscores the importance of continuous global surveillance and research to better predict and respond to future influenza outbreaks. This study provides scientific evidence for the development of more effective vaccines and influenza control strategies, thereby enhancing global public health response capabilities.

Keywords
Influenza virus; Evolutionary mechanisms; Antigenic drift; Antigenic shift; Immune evasion; Vaccine development

(The advance publishing of the abstract of this manuscript does not mean final published, the end result whether or not published will depend on the comments of peer reviewers and decision of our editorial board.)
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International Journal of Super Species Research
• Volume 14
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